FDA & Rare Disease Breakthrough: Ionis’ ZANVASTRO (zilganersen) has received FDA approval as the first and only disease-modifying treatment for Alexander disease in both pediatrics and adults, with companies outlining launch strategy. Infectious Disease & Research: Liverpool launched a £20m high-security AI lab aimed at speeding up drug and vaccine discovery for high-risk infections, with full opening expected in 2027. Alzheimer’s & Sleep Science: A Concordia-led study links sleep brain waves to slower cognitive decline in mild-to-moderate Alzheimer’s, suggesting “neural resilience” tied to specific patterns during NREM sleep. Public Health Alerts: San Diego County warned guests of Gaylord Pacific Resort about possible cryptosporidium exposure from pools used in late July/early August. Rural Care Funding: New York announced $76m for rural healthcare partnerships and workforce support across 56 organizations. Healthcare Access Under Pressure: West Volusia Hospital Authority warned a proposed property tax change could cut funding by millions, forcing difficult budget tradeoffs. Workforce & Culture: A California family story highlights three generations of nurses with 40 years of service at one hospital. Community Drug Safety: Ontario’s Grand Erie health unit extended a drug alert after rising suspected overdose deaths and ER visits, urging naloxone and caution with unregulated supplies.